What is Naltrexone?

Naltrexone is a prescription medication primarily used in the treatment of opioid and alcohol dependence. It works by blocking opioid receptors in the brain, which prevents the euphoric and sedative effects typically associated with opioids. This mechanism helps reduce the potential for misuse and relapse in individuals recovering from opioid addiction.

Naltrexone is available in both oral tablet form (commonly known as Revia) and an extended-release injectable form (Vivitrol), which is administered once a month. The extended-release version helps improve adherence by eliminating the need for daily dosing, which can be a barrier for some patients in recovery.

Beyond opioid addiction, Naltrexone is also used to support recovery from alcohol use disorder. It can decrease the desire to drink by blocking the endorphins released when alcohol is consumed, which diminishes the reinforcing effects of alcohol.

Unlike methadone or buprenorphine, Naltrexone is not a controlled substance and does not carry a risk of physical dependence. This makes it a valuable option in medication-assisted treatment (MAT) programs, especially for individuals looking to maintain complete abstinence from all opioids.